General description

Structure of the Rhodopsin-Transducin Complex

PDB ID: 6OY9 RCSB | OPM

Receptor name: Rhodopsin

Receptor chain: R

Receptor organism: Bos taurus

Family / Class: Rhodopsin-like / A

Resolution [Å]: 3.9

Effector protein: G: α β γ (A B G)

Non-peptide ligand code: RET (R)


MD preparation

Mutations

Number of mutations: 0

List of mutations: None

Receptor
Receptor

Name: Rhodopsin

Organism: Bos taurus

Uniprot: P02699

Effector protein

Name: Guanine nucleotide-binding protein G(t) subunit alpha-1

Organism: Homo sapiens

Uniprot: P63092

Name: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

Organism: Homo sapiens

Uniprot: P62873

Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2

Organism: Homo sapiens

Uniprot: P59768

References

Title: Structures of the Rhodopsin-Transducin Complex: Insights into G-Protein Activation.

Authors: Gao Y, Hu H, Ramachandran S, Erickson JW, Cerione RA, Skiniotis G

Published: Mol Cell (2019)

Receptor TM helicies
TM regions (from OPM database)

TM1( 38-60),TM2( 74-99),TM3( 109-134),TM4( 153-172),TM5( 201-224),TM6( 253-274),TM7( 286-309)

Additional info

Membrane Thickness: 31.8 ± 1.2 Å

Tilt: 6 ± 0°


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